Lund University
Dept of Clinical Sciences Malmö
Diabetes and endocrinology
CRC, Jan Waldenströms gata 35, building 60, floor 13
SUS Malmö
SE-205 02  Malmö, Sweden


Jenny Vikman

Associated researcher

Pregnancy alters the normal balance that regulates glucose metabolism and insulin secretion and results in an increased insulin resistance in fat and muscle followed by a compensatory increase in insulin production and secretion as well as proliferation and adaptation of beta cells in the islets. The mechanisms that underlie the adaptation and expansion of beta cell mass have only been investigated to a small extent.

Since pregnancy induces such marked change in the islets that could compensate for the increased demand it would be of great benefit to survey these changes.

Research focus

  • Identify genes that are important for islet adaptation and proliferation during pregnancy in mouse models
  • Perform functional analysis of important key proteins and signaling pathways that is diversely regulated during pregnancy
  • Evaluate the impact of nutrition on islet adaptation during pregnancy in mouse models.

Last updated: October 23, 2014
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LUDC, CRC, SUS Malmö, Entrance 72, House 91:12. SE-205 02 Malmö. Telephone: +46 40 39 10 00