Associate Researcher

Current project

Role of non-protein coding RNAs (ncRNAs: miRNAs, lincRNAs, snoRNAs, piRNAs, etc) in various aspects of diabetes, and exploring their potential as novel therapeutic targets.

miRNAs as blood-based biomarkers in the progression of T2D and associated complications

Academic degree

PhD in Microbiology (focus in Functional Genomics), October 2008, University of Gothenburg
(Thesis: High-resolution phenotypic profiling of a eukaryotic ribosome, pdf)

Licentiate in Microbiology, August 2006, University of Gothenburg

M.Sc. in Bioinformatics, December 2002, Chalmers University of Technology
(Thesis: Putative Lewis^b-binding site of Helicobacter pylori blood-group antigen-binding adhesin (BabA) revealed by knowledge-based homology modeling

B.Sc. Molecular Biology and Biotechnology, 1998, University of the Philippines-Diliman
 

Publications

Articles Indexed at Pubmed

Published conference proceedings

King BCR, Esguerra J, Eliasson L, Cardone J, Kemper C, Blom AM. MicroRNA profiles of CD46-stimulated T cells. Molecular Immunology, Volume 48, Issue 14, August 2011, Page 1691. XIII European Meeting on Complement in Human Disease Leiden, The Netherlands, August 21st–24th 2011.

Andersson SA, Olsson AH, Esguerra JL, Ladenvall C, Salehi AS, Taneera J, Groop L, Ling C,  Eliasson L. Reduced expression of genes involved in exocytosis in type 2 diabetic human islets. Diabetologia. 2011; 54(Suppl 1):S20. 47th Annual Meeting of the European Association for the Study of Diabetes. Lisbon, Portugal.

Esguerra JLS, Bolmeson C, Cillio M, Eliasson L. Impaired glucose-regulated microRNAs in the pancreatic islets of the non-obese type 2 diabetes model Goto-Kakizaki rats. Acta Physiologica. 2010; 198(Suppl 677):S-SAT-1-8. Joint Meeting of the Scandinavian and German Physiological Societies. Copenhagen, Denmark.

Esguerra J, Bolmeson C, Cillio M, Eliasson L. Predicted targets of co-expressed microRNAs in pancreatic islets of GK rats are enriched for genes involved in regulation of beta cell mass and glucose-stimulated insulin secretion. Diabetologia. 2009; 52(Suppl 1):391. 45th Annual Meeting of the European Association for the Study of Diabetes. Vienna, Austria.

Citation report

@GoogleScholar: Jonathan LS Esguerra

Funding

EFSD/Lily Research Fellowship
Crafoord Foundation