Role of non-protein coding RNAs (ncRNAs: miRNAs, lincRNAs, snoRNAs, piRNAs, etc) in various aspects of diabetes, and exploring their potential as novel therapeutic targets.
miRNAs as blood-based biomarkers in the progression of T2D and associated complications
PhD in Microbiology (focus in Functional Genomics), October 2008, University of Gothenburg
(Thesis: High-resolution phenotypic profiling of a eukaryotic ribosome, pdf)
Licentiate in Microbiology, August 2006, University of Gothenburg
M.Sc. in Bioinformatics, December 2002, Chalmers University of Technology
(Thesis: Putative Lewisb-binding site of Helicobacter pylori blood-group antigen-binding adhesin (BabA) revealed by knowledge-based homology modeling
B.Sc. Molecular Biology and Biotechnology, 1998, University of the Philippines-Diliman
Salunkhe VA, Andersson SA, Esguerra JLS, Mollet IG, Wendt A, Eliasson L. Regulation of miR-335 expression contributes to orchestrate insulin-secretion at the level of exocytosis in insulin secreting INS-1 832/13 cells. Diabetologia. 2013; 56 (Suppl 1):S198. 49th Annual Meeting of the European Association for the Study of Diabetes. Barcelona, Spain.
Malm H, Mollet I, Esguerra JLS, Orho-Melander M, Eliasson L. cAMP-mediated regulation of miR-212/132 expression in insulin-secreting cells acts through CREB-regulated transcription co-activator 1 (CRTC1). Diabetologia. 2013; 56 (Suppl 1):S504. 49th Annual Meeting of the European Association for the Study of Diabetes. Barcelona, Spain.
King BC, Esguerra J, Qayyum M, Eliasson L, Kemper C, Blom AM. Immunobiology, Volume 217 Issue 11, November 2012, Pages 1148-1149. XXIV International Complement Workshop. Chania, Crete, Greece.
Salunkhe VA, Braun M, Esguerra JLS, Mollet I, Wendt A, Stoffel M, Rorsman P, Eliasson L. Influence of miR-375 on electrophysiological properties of voltage-dependent Na+ channels in mouse beta cells and INS-1 832/13 cells. Diabetologia. 2012; 55 (Suppl 1):S204. 48th Annual Meeting of the European Association for the Study of Diabetes. Berlin, Germany.
King BCR, Esguerra J, Eliasson L, Cardone J, Kemper C, Blom AM. MicroRNA profiles of CD46-stimulated T cells. Molecular Immunology, Volume 48, Issue 14, August 2011, Page 1691. XIII European Meeting on Complement in Human Disease Leiden, The Netherlands, August 21st–24th 2011.
Andersson SA, Olsson AH, Esguerra JL, Ladenvall C, Salehi AS, Taneera J, Groop L, Ling C, Eliasson L. Reduced expression of genes involved in exocytosis in type 2 diabetic human islets. Diabetologia. 2011; 54(Suppl 1):S20. 47th Annual Meeting of the European Association for the Study of Diabetes. Lisbon, Portugal.
Esguerra JLS, Bolmeson C, Cillio M, Eliasson L. Impaired glucose-regulated microRNAs in the pancreatic islets of the non-obese type 2 diabetes model Goto-Kakizaki rats. Acta Physiologica. 2010; 198(Suppl 677):S-SAT-1-8. Joint Meeting of the Scandinavian and German Physiological Societies. Copenhagen, Denmark.
Bolmeson C, Esguerra JLS, Speidel D, Eliasson L, Cilio CM. MicroRNA differences in human islets and glucose-sensitive tissues. Diabetologia. 2010; 53(Suppl 1):S214. 46th Annual Meeting of the European Association for the Study of Diabetes. Stockholm, Sweden.
Esguerra J, Bolmeson C, Cillio M, Eliasson L. Predicted targets of co-expressed microRNAs in pancreatic islets of GK rats are enriched for genes involved in regulation of beta cell mass and glucose-stimulated insulin secretion. Diabetologia. 2009; 52(Suppl 1):S162. 45th Annual Meeting of the European Association for the Study of Diabetes. Vienna, Austria.
@GoogleScholar: Jonathan LS Esguerra
EFSD/Lily Research Fellowship
Last updated: January 9, 2014
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